in sickle-cell anemia valine replaces glutamic acid in the β-chain
Answers
Sickle-cell anemia is an inherited blood disorder that causes red blood cells to become deformed and rigid, resulting in a lack of oxygen supply to organs and tissues. This is due to a mutation in the β-globin gene on chromosome 11, which encodes the β-chain of hemoglobin.
In sickle cell anemia, a substitution of valine for glutamic acid occurs in the sixth position of the β-chain of hemoglobin. This substitution results in the formation of abnormal hemoglobin called hemoglobin S, which causes the red blood cells to become stiff and misshapen when oxygen levels are low.
The β-chain of hemoglobin is a protein made up of 146 amino acids. The sixth amino acid in the β-chain is normally glutamic acid. However, in sickle cell anemia, a single nucleotide substitution in the β-globin gene causes the sixth amino acid to be replaced by valine.
As a result, the hemoglobin protein is altered, leading to the formation of sickle-shaped red blood cells that are prone to clumping together and blocking small blood vessels.
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Related Questions
You have a plant that you want to show off at a party. The party happens during autumn (aka fall). Usually in autumn (aka fall) the leaves of your plant fall off. You want to delay the leaves falling off your plant until after the party. What plant hormone would you use to help keep the leaves on? ethylene O cytokinins O gibberellins auxin
Answers
Answer:
Auxins
Explanation:
Auxin is a plant hormone that has to do with both leaf and fruit fall.
A sample of liquid water is boiling. As more heat is added, the temperature of the liquid water will
Answers
Answer:
increase
Explanation:
Answer: It will increase
Explain: When the water tempter gets higher the water starts to increase due to the heat.
I hope this help! have a nice day!
Which structure would not be found in a prokaryotic cell?
O cell wall
O cell membrane
O cytoplasm
O nucleus
Answers
Answer: Nucleus as prokaryotes don't have their DNA enclosed in the nucleus unlike eukaroytes. They contain a single loop of dna and have no Nucleus
Answer:
Nucleus
Explanation:
Prokaryotic cells have a capsule, ribosomes, DNA, cell wall, Plasma membrane, and cytoplasm. However, A nucleus is only present in eukaryotic cells.
Which apgar score indicates a moderately depressed newborn that requires stimulation and oxygen?
Answers
An Apgar score of 4-6 indicates a moderately depressed newborn that requires stimulation and oxygen. The Apgar score is a quick assessment conducted immediately after birth to evaluate the newborn's overall health and well-being.
It measures five specific criteria: heart rate, respiratory effort, muscle tone, reflex irritability, and color. Each criterion is scored on a scale of 0 to 2, with a maximum total score of 10.
A score of 4-6 on the Apgar scale suggests moderate depression in the newborn. This indicates that the baby may require assistance to stimulate their breathing and may also need supplemental oxygen. The medical professionals present at the birth would closely monitor the newborn's condition and provide appropriate interventions to support their transition to normal breathing and oxygenation.
It's important to note that the Apgar score is just one tool used to assess a newborn's initial condition, and additional medical evaluations and interventions may be necessary based on the individual circumstances and the baby's ongoing well-being.
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Experiments Explain the 4 properties of water shown in this picture
Explanation
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An orchid is found in the lower canopy of a tropical rain forest. It does not grow from the ground but grows on a tree. Therefore , an orchid is an :
Answers
Answer:
Epiphyte
Explanation:
The correct answer would be an epiphyte.
An epiphyte is a plant that grows on another plant for support only. Epiphytic plants are capable of manufacturing its own food using photosynthesis and perform every other life processes independently but only depend on another plant for anchorage. All their material requirements such as water and minerals are derived from the air surrounding them.
Define polar molecule or polarity.This is not a test question, could you please simplify the response to as few sentences as possible?
Answers
Polarity is caused by electronegativity. Electronegativity is the ability of an atom to attract electrons and when in a molecule there is a region of low electronegativity and a region of high electronegativity we say that the molecule is polar.
Some form of early Homo is estimated to have evolved into Homo erectus around: O 5-7.5 million years ago
O 1.7-2 million years ago O 10,000-40,000 years ago O 50,000-70,000 years ago t
Answers
Some form of early Homo is estimated to have evolved into Homo erectus around 1.7-2 million years ago, option B is correct.
Homo erectus is believed to have evolved around 1.7-2 million years ago based on fossil evidence and dating methods. Fossil discoveries, such as the famous Nariokotome Boy skeleton found in Kenya, provide crucial insights into the anatomy and characteristics of Homo erectus. These fossils, along with other archaeological and genetic evidence, suggest that Homo erectus was the first hominin species to exhibit significant anatomical and behavioral differences from earlier hominins.
The emergence of Homo erectus marked a significant milestone in human evolution, as this species had a larger brain size, more advanced tool-making abilities, and potentially even the ability to control fire. These developments laid the foundation for the subsequent evolution of Homo sapiens, option B is correct.
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The complete question is:
Some form of early Homo is estimated to have evolved into Homo erectus around:
A) 5-7.5 million years ago
B) 1.7-2 million years ago
C) 10,000-40,000 years ago
D) 50,000-70,000 years ago
Place the options in the correct spot of an earthquake.
Answers
The correct order of the options in an earthquake, from the top to bottom, is: Epicenter, Focus/Hypocenter, Seismic waves, Fault.
What is an earthquake's epicentre?The tectonic plate border is where the earthquakes start. The epicentre, which is the point on the earth's surface just above the focus, is frequently referred to as the hypocenter because it is the location inside the earth where the earthquake began.
What does focus and epicentre mean?The focal point is the location where an earthquake begins within the crust of the Earth. The epicentre is a location on the surface of the Earth that is directly above the focus. Seismic waves radiate outward in all directions from the focus, when energy is released.
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the production of pepsinogen as an inactive proenzyme is an adaptation that most likely provides which evolutionary advantage?
Answers
The production of pepsinogen as an inactive proenzyme is an important adaptation that provides several evolutionary advantages, including protecting the stomach lining and allowing for a more versatile diet.
The production of pepsinogen as an inactive proenzyme is an adaptation that most likely provides an evolutionary advantage by protecting the stomach lining from the harsh digestive enzymes it produces. Pepsinogen is produced by the chief cells of the stomach and is converted to pepsin, an enzyme that breaks down proteins, by the acidic environment of the stomach. However, if pepsinogen were not produced as an inactive proenzyme, it would also be activated within the chief cells and damage them.
This adaptation allows for the controlled release of pepsin, only when it is needed for digestion, and prevents it from causing harm to the stomach lining. This allows for more efficient digestion and absorption of nutrients, which could have provided an advantage in the evolutionary process.
Furthermore, the production of pepsinogen as an inactive proenzyme allows for a more versatile diet, as it allows for the digestion of proteins from a wider range of sources. This would have been beneficial in environments where food sources were limited or unpredictable, allowing for a greater chance of survival and reproduction.
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A piece of wood weighs 72 g. What is its density
if its volume is 20 cm'?
Answers
Answer:
desnity is equal weight divided by volume ,so 72/20= 3.6
Explanation:
Hope this helps
A quantity must be divided by multiples of ten when converting from a larger unit to a smaller unit.
Please select the best answer from the choices provided
Ot
Of
Answers
The statement that a quantity must be divided by multiples of ten when converting from a larger unit to a smaller unit is true.
Is it true or false?A conversion factor is a numerical factor that is used to change the unit of measurement of a quantity. It comes from how the two units of measurement relate to one another. Usually, conversion factors are ratios of identical values represented in several units.
It is true that there are sometimes that we need to convert from a larger to a smaller unit and in that case we have to use the multiples of ten for the calculation as shown above.
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What gave the smooth ER its name?
Answers
The smooth endoplasmic reticulum (smooth ER) got its name due to its appearance under an electron microscope.
Unlike the rough endoplasmic reticulum, which has ribosomes attached to its surface giving it a rough texture, the smooth ER has a continuous, smooth membrane without ribosomes. This membrane-bound organelle plays a crucial role in lipid synthesis, metabolism, and detoxification of drugs and toxins. It also helps regulate calcium ions in the cell and participates in the breakdown of glycogen.
This structure allows the smooth ER to perform specific functions, such as lipid and steroid synthesis, detoxification of harmful substances, and calcium ion storage. The absence of ribosomes and its associated smooth appearance led scientists to name this organelle the smooth endoplasmic reticulum.
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one way to describe and understand the biological connection between humans and other animals is
Answers
One way to describe and understand the biological connection between humans and other animals is as examples of ecological interactions that involve three widely used symbioses.
Any sort of close and sustained biological contact, whether mutualistic, commensalist, or parasitic, is referred to as symbiosis. Each of the creatures, referred to as symbionts, must be from a distinct species. It was described as "the living together of unlike organisms" by Heinrich Anton de Bary in 1879. A century-long argument ensued about the term's appropriateness to particularly refer to mutualism, such as that found in lichens. Now, biologists have given up on that limitation.
Symbiosis can be facultative, in which case the symbionts can normally survive independently, or obligatory, in which case one or more of the symbionts are dependent on one another for survival.
Physical attachment is another way to categorize symbiosis. Conjunctive symbiosis refers to the formation of a single body by symbionts, whereas disjunctive symbiosis refers to all other configurations.
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NEED HELP DUE TODAY PLZ HELP ME I AM STUCK PLZ PLZ PLZ HELP ME!!!!
Nucleoside reverse transcriptase inhibitors (NRTIs) are a class of drugs used to treat human immunodeficiency virus (HIV). Unfortunately, a major side effect of these drugs causes people to get tired very easily, often due to a lack of energy.
Which of the following choices would be the best explanation as to the cause of this drug's side effect?
Choose 1 answer:
(Choice A)
A
The drug may be toxic to mitochondria, organelles that provide a source of energy (ATP) for the cell.
(Choice B)
B
The drug may be toxic to the Golgi body, an organelle that receives, modifies, and transports cellular materials.
(Choice C)
C
The drug may be toxic to the endoplasmic reticulum (ER), an organelle that provides a source of energy (ATP) for the cell.
(Choice D)
D
The drug may be toxic to lysosomes, organelles that enzymatically break down cellular wastes.
Answers
(1) What is the most common way for a dead organism to avoid decomposition?
(2) Why do researchers look for fossils in places that are now dry and barren instead of
other places like forests or grasslands?
(3) What kind of dating from the lecture or textbook would be the best method for finding
the number of years ago when a volcanic rock was formed?
(4) Why is the pelvis of a biped shorter and wider than the pelvis of a quadruped?
(5) Does the overall shape of Lucy’s pelvis resemble the human pelvis or the chimpanzee pelvis more? Do not think of the size, but compare the outlines of each bone
Answers
Answer:
The body could be buried in a sandstorm.The body could be buried by water action.The body could be covered by ash from an erupting volcano.The body could be buried by an animal.Dry and barren places have high erosion that reveals fossils.Dry and barren places are comfortable for heavy phyiscal labor.Prehistoric life only lived in dry and barren places.Dry and barren places have always been the same environment.Radiopotassium dating.Amino acid racemization dating.
Genetic distance dating.
Radiocarbon dating.
4. The biped's pelvis is adapted to hold more body weight
The biped pelvis has to have room for a tail.
The biped pelvis only has to support the leg muscles. The biped pelvis connects to all four limbs.
5.Lucy's pelvis resembles the chimpanzee pelvis more.
Lucy's pelvis resembles the human pelvis more.
Explanation:
if it helped uh please mark me a BRAINLIEST :)
Which of the following human impacts could cause Eutrophication of water bodies? Deforestation farming burning fossil fuels or all of the above
Answers
A process known as eutrophication is brought on by an excess of nutrients, primarily nitrogen and phosphorus, in water. Algae thrive, spread, and color the water green as a result of feeding on the nutrients.
Which 3 human factors contribute to eutrophication?Because of human activities, cultural eutrophication is a process that accelerates natural eutrophication. The three primary sources for anthropogenic nutrient input are sewage form cities and industrial waste water, as well as erosion and leakage from fertilized agricultural areas.
Use of fossil fuels in deforestationMore carbon dioxide is now accumulating in the atmosphere as a result of burning fossil fuels than can be absorbed by current carbon sinks like forests, as well as the loss of carbon sinks from deforestation and other activities.
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A concept is the general idea of objects, events, animals, or people based on common features, traits, or characteristics. Please select the best answer from the choices provided T /F
Answers
The statement "A concept is the general idea of objects, events, animals, or people based on common features, traits, or characteristics" is true.
A concept can be defined as a general idea or understanding of something based on common features, traits, or characteristics that it shares with other things. It can apply to objects, events, animals, or people, as well as abstract ideas such as emotions, theories, or beliefs.
For example, the concept of "animals" is based on their shared characteristics of being living creatures that move, breathe, and reproduce.
A concept is indeed the general idea or mental representation of objects, events, animals, or people based on their common features, traits, or characteristics. It helps us categorize and understand the world around us by grouping similar things together based on shared properties.
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Yooo is Fire a living thing?
Answers
Answer:
no
Explanation:
it wouldn't be ideal to define fire as a living thing because it doesn't possess the characteristics of living things.
An organism that must consume other organisms for energy is a
Answers
Answer:
A consumer of energy
Explanation:
In what way have humans been applying the principles of heredity for millennia?.
Answers
Humans have been applying the principles of heredity for millennia. They have been able to control the breeding of animals and plants since ancient times. They chose the best animals or plants to breed, ensuring that their offspring will have desirable traits or characteristics.
Over time, they were able to improve the yields of crops and the quality of livestock through selective breeding. In addition, people have also applied the principles of heredity to themselves through selective breeding in humans. They chose partners with desirable traits and characteristics to produce offspring with these same qualities.Long answer:Humans have applied the principles of heredity in several ways throughout history. One of the earliest examples is the domestication of animals, where humans selectively bred wild animals with desirable traits to create a new breed. This process has resulted in a wide variety of domesticated animals, such as dogs, cats, and horses. People also selectively bred plants for desirable traits, leading to the development of many new plant varieties.In addition, humans have used heredity principles to improve the quality of livestock. For example, farmers may breed cows with the best milk production or bulls with the best meat quality.
This selective breeding has resulted in increased yields and improved quality of livestock over time.Similarly, humans have applied heredity principles to themselves. In many cultures, people used to practice selective breeding by choosing partners with desirable traits to produce offspring with these same qualities. For example, ancient Egyptian pharaohs practiced sibling marriage to keep the royal bloodline pure. In some cultures, there were even laws that mandated the selection of marriage partners with specific traits, such as intelligence or physical strength.Today, humans continue to apply the principles of heredity in a variety of ways. Genetic engineering, for example, allows scientists to manipulate genes to produce desired traits in plants and animals. This has led to the development of new crop varieties that are resistant to pests or tolerant of drought conditions. It has also led to the creation of new breeds of animals with desirable traits, such as glow-in-the-dark fish.Overall, the principles of heredity have been applied by humans for thousands of years to improve the quality and productivity of crops and livestock and even to enhance human qualities Humans have been applying the principles of heredity for millennia. They have been able to control the breeding of animals and plants since ancient times. They chose the best animals or plants to breed, ensuring that their offspring will have desirable traits or characteristics Over time, they were able to improve the yields of crops and the quality of livestock through selective breeding. In addition, people have also applied the principles of heredity to themselves through selective breeding in humans. They chose partners with desirable traits and characteristics to produce offspring with these same qualities.
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Identify one of the leadership values you would like to develop further over the course of the next year and propose an improvement plan (tasks, dates, measures of progress). Your plan should be specific, measurable, achievable, relavant and time bound. Leadership values are discussed in Chapter 7 of the text and you can find examples and lists through your own research. These values tend to define your "personal character" or "personal brand" and should be consistent with you actions and behaviour. Examples would include: honesty, hardworking, trustworthy, ethical, loyal, persistent, optimistic, motivating, encouraging, brave, caring, respectful, give and take responsibility, admit to mistakes and learn, accountable, reliable, keep promises, listen and coach others, take initiative, proactive, maintain stamina, positive attitude, etc.
Answers
By following this improvement plan,one can aim to develop and enhance my empathy as a leadership value over the next year.
One leadership value I would like to develop further over the course of the next year is empathy. Empathy is a crucial leadership trait that involves understanding and sharing the feelings of others. It allows leaders to connect with their team members on a deeper level, foster positive relationships, and create a supportive work environment.
Improvement Plan for Developing Empathy:
Research and Study: (July - August): Read books and articles on empathy and its importance in leadership.Attend webinars or workshops focused on developing empathy skills.Engage in discussions with colleagues or mentors who possess strong empathetic qualities.Self-Assessment: (September): Reflect on my current level of empathy and identify areas for improvement.Evaluate past interactions with team members to identify instances where empathy could have been enhanced.Take note of personal biases or preconceptions that may hinder empathetic responses.Active Listening: (October - November): Practice active listening skills, focusing on truly understanding others without interrupting or judging. Demonstrate genuine interest in others' thoughts, feelings, and perspectives. Engage in conversations where I actively seek to understand rather than merely respond.Emotional Intelligence Development: (December - January): Enhance emotional intelligence by recognizing and managing my own emotions effectively. Develop a better understanding of how emotions impact the behavior and well-being of others. Explore strategies for regulating emotions and responding empathetically in challenging situations.Perspective-Taking: (February - March): Put myself in others' shoes to gain a deeper understanding of their experiences, challenges, and motivations.Seek opportunities to learn about the diverse backgrounds and perspectives of team members. Encourage open dialogue and create a safe space for team members to share their thoughts and feelings.Feedback and Reflection: (April - May): Seek feedback from colleagues, team members, and mentors regarding my progress in demonstrating empathy. Reflect on my interactions and evaluate how well I have applied empathy in different situations. Make adjustments based on feedback and continue to refine my empathetic approach.Measures of Progress: Regularly self-assess my empathetic responses and behaviors. Seek feedback from team members regarding their perception of my empathy. Notice an increase in open and honest communication within the team. Observe improved trust, engagement, and satisfaction among team members. Evaluate the frequency and quality of personal connections and relationships established with team members.By following this improvement plan,one can aim to develop and enhance my empathy as a leadership value over the next year.
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Which best explains why water has a high specific heat?
O Hydrogen bonds decrease the amount of energy that is required for the temperature to change.
O Hydrogen bonds increase the amount of energy that is required for the temperature to change.
Olon-dipole interactions increase the amount of energy that is required for the temperature to change.
O lon-dipole interactions decrease the amount of energy that is required for the temperature to change
Answers
Answer: B. is the answer, I believe.
The sentence which explains why water has a high specific heat is: B. hydrogen bonds increase the amount of energy that is required for the temperature to change.
What is hydrogen bond?Hydrogen bond can be defined as a weak type of chemical bond (intermolecular force) which exist between a partially positively charged hydrogen atom and an electronegative chemical atom.
Based on scientific information, the sentence which best explains the reason why water has a high specific heat is that hydrogen bonds increases the quantity of energy that is required for the temperature of water to change.
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a cell that keeps its dna in a membrane-bounded nucleus could be a cell from which organisms?
Answers
Answer:
It could be the cell from animals.
Predict the genotypic ratios of the offspring from crossing the following:
Tt x Tt
1:2:1
3:1
9:3:3:1
1:4
Answers
Answer:
1:2:1
Explanation:
1 chance of having the genotype TT
2 chances of having the genotype of Tt
1 chance of having the genotype of tt
In science when writing an explanation what must include
Answers
Answer:
Our scientific explanation framework consists of four components: (1) claim, (2) evidence, (3) reasoning,1 and (4) rebuttal.
Explanation
which age of rocks are missing in NYS?
Answers
Answer:
Adirondacks "Missing Time" Formation
According to the Nebular Theory, the solar system began as a large, slowly rotating cloud of gas about one light-year in size. As the cloud cooled, it collapsed due to its own gravity. Conservation of angular momentum caused it to distort into a rotating pancake shape because it had to spin faster as it shrank. Then the Sun began to form at the center, and rings formed around the Sun. Next the rings coalesced into planets. Two problems with the old Nebular Theory are: (i) rings would not form around the Sun; (ii) Planets would not form because the gas pressure would be too high.
Answers
Immanuel Kant and Pierre-Simon Laplace both contributed to the growth of the Nebular Theory, an early theory that attempted to explain how the solar system formed. Although it served as a basis for comprehending how stars and planetary systems develop,
The concerns you stated were among the difficulties the theory had in attempting to explain certain elements of the development of the solar system:
(i) Rings would not form around the Sun: According to the original Nebular Theory, rings would develop around the Sun when planets formed. The study of rings around gas giants like Saturn, however, made it clear that they are not a fundamental or common element of planetary formation. It is thought that the disruption of moons or other tiny things within the planet's gravitational field causes rings to form around gas giants.
(ii) The original Nebular Theory postulated that planets originated from the coalescence of gas and dust within the revolving disc around the young Sun. However, gas pressure would be too high for planet formation. It was understood, nonetheless, that the protoplanetary disk's gas pressure would prevent the agglomeration of solid particles into bigger entities. The contemporary theory of planetesimal accretion, which describes how small solid particles progressively cluster together through collisions and gravitational attraction to become bigger things termed planetesimals, which then continue to expand to become planets, was developed to solve this issue.
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A couple are expecting a baby. They already have a daughter.
a) What is the probability their next child will also be a girl?
b) Explain your answer.
Answers
Answer:
50/50
Explanation:
u never know if it will be a girl or a boy because it is natural to either one
HOPE THIS HELPS
Answer:50/50
Explanation:
it doesn't matter how many children you have or what gender they are you will always have a 50% percent chance
Each of the following hormones is produced by the placenta except one. Identify the exception.
A. human placental lactogen (hPL)
B. progesterone
C. LH
D. human chorionic gonadotropin (hCG)
E. relaxin
Answers
The exception among the given hormones that are produced by the placenta is LH (luteinizing hormone).
Among the hormones listed, LH (luteinizing hormone) is the exception as it is not produced by the placenta. The placenta, which is an organ that develops during pregnancy, plays a crucial role in hormone production to support the growth and development of the fetus.
It produces several hormones, including human placental lactogen (hPL), progesterone, human chorionic gonadotropin (hCG), and relaxin. These hormones are involved in maintaining pregnancy, regulating fetal growth, and preparing the body for childbirth.
LH, on the other hand, is a hormone primarily produced by the pituitary gland in both males and females. In females, LH plays a key role in the menstrual cycle, triggering ovulation and stimulating the production of progesterone by the ovaries. While the placenta produces various hormones necessary for a healthy pregnancy, LH production remains primarily in the domain of the pituitary gland rather than the placenta.
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